The automated control system ofoverhead crane-manipulator electric drivesfor metals decontamination plant was developed. The craneconstruction and electric drivesdisposition are presented. The functional and electrical schemeswere developed. The crane electric drives, position-measuring systems, programmable logic controllers, and PC workstation were selected. The problem of wheelssynchronous rotation when moving the trolley and the bridge, as well as the problem of exact positioning of all cranemechanisms were solved. The control algorithm, program and SCADA system weredeveloped.Control cabinet for crane-manipulator was produced.